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J Cardiovasc Pharmacol 34(5):690693

Interleukin 1 stimulates platelet-activating factor production in cultured human endothelial cells

Supersulfides are highly reactive and biologically potent molecules that function as antioxidants, redox regulators, and modulators of cell signaling

For example, it has demonstrated pro-estrogenic effects on bone and anti-estrogenic effects on breast tissue, although its safety in women with breast cancer has not yet been confirmed

But, oxidative damage has been recently documented as an initiating event responsible for different genotoxic and cytotoxic effects of ZON (Figure 1) (119)